吸烟会增加人类的同情力外流
K Narkiewicz1, P J van de Borne, M Hausberg
1Department of Internal Medicine, University of Iowa College of Medicine, Iowa City 52242, USA.
Circulation
|August 26, 1998
概括
吸烟显著增加了同情神经活动 (SNA),与以前的信念相反. 这项研究表明,吸烟直接增加了同情的外流,影响心血管健康.
科学领域:
- 心血管生理学心血管生理学
- 自主神经系统研究 自主神经系统研究
- 吸烟和健康研究研究
背景情况:
- 众所周知,吸烟会提高血压.
- 以前的研究表明,吸烟会降低肌肉交感神经活动 (SNA).
- 这种下降可能是由于巴罗反射反应,掩盖了吸烟对同情外流的真正影响.
研究的目的:
- 为了测试吸烟会增加同情力外流的假设.
- 研究吸烟对同情神经系统的直接影响.
主要方法:
- 在健康吸烟者中检查肌肉 (依赖巴罗反射) 和皮肤 (依赖巴罗反射) SNA.
- 假冒吸烟,香烟吸烟和吸烟与尼托普鲁塞德相比较的影响,以减轻血压反应.
- 在受控实验中利用侵入性SNA测量.
主要成果:
- 仅仅吸烟就会增加血压,并减少肌肉SNA.
- 当吸烟的压力效应被尼托普鲁塞德减弱时,肌肉SNA增加了三倍.
- 皮肤SNA也显示在吸烟后显著增加 (102%).
结论:
- 吸烟直接增加了同情的外流.
- 提供了吸烟对同情神经系统刺激作用的第一个直接证据.
- 突出了吸烟,血压和同情活动之间的复杂相互作用.
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