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Updated: Jun 18, 2026

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay
13:10

Detection and Visualization of DNA Damage-induced Protein Complexes in Suspension Cell Cultures Using the Proximity Ligation Assay

Published on: June 9, 2017

通过RAG1和RAG2蛋白进行DNA转换:可能是致癌转位的来源

K Hiom1, M Melek, M Gellert

  • 1Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892-0540, USA.

Cell
|September 4, 1998
PubMed
概括

RAG1和RAG2蛋白质启动V(D) J重组,也可以移动DNA段,这表明免疫系统是从移动DNA元素进化而来的. 这种转位活动可能解释了淋巴瘤中某些DNA转位.

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Visualization and Quantitative Analysis of Genotoxin-Induced PARP1/PARP2 Activation in Cells Using a Fluorescent Fusion Protein-Based Reporter07:53

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