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Quantitative Autonomic Testing
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血管之前的心肺呼吸动态的复杂解调
L A Lipsitz1, J Hayano, S Sakata
1Hebrew Rehabilitation Center for Aged Research and Training Institute, Department of Medicine, Harvard Medical School, Boston, Mass 02131, USA. Lipsitz@mail.hrca.harvard.edu
Circulation
|September 16, 1998
概括
血管综合症涉及复杂的自主性变化,包括呼吸加快和昏前阴道音调突然升高. 这表明心肺呼吸系统脱之前的心率急剧下降导致昏迷.
科学领域:
- 心脏病学 心脏病学
- 自主神经科学 自主神经科学
- 呼吸系统生理学 呼吸系统生理学
背景情况:
- 自主神经系统在血管失眠中的作用尚未完全理解.
- 血管缩是一种常见的疾病,其特点是血压和心率的突然下降.
研究的目的:
- 为了研究之前的动态自主过程倾斜诱导的血管.
- 分析健康个体昏迷前心肺呼吸系统变异性的变化.
主要方法:
- 复杂的解调被用来评估呼吸,R-R间隔,并在头向上倾斜时的动脉压变化.
- 一致性和转移功能分析检查了呼吸和R-R间隔变化之间的关系.
- 研究了25名昏睡的健康受试者和25名对照人.
主要成果:
- 昏迷患者在昏迷前3分钟表现出潮体积增加和血压降低.
- 阴道音调突然增加 (延长R-R间隔,增加可变性) 发生在昏迷前90秒.
- 观察到心肺呼吸道脱,呼吸和R-R间隔变异性之间的连贯性减少.
结论:
- 血管之前是呼吸过敏和心肺呼吸系统脱.
- 心血管音调的急剧增加和随后的白心骤然缩.
- 呼吸系统的变化可能最初会抵消降低的预负载,直到突然发生心梗塞.
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