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慢性多症状疾病影响海湾战争空军退伍军人
K Fukuda1, R Nisenbaum, G Stewart
1Division of Viral and Rickettsial Diseases, National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA.
海湾战争 (GW) 退伍军人比未部署的同龄人更频繁地经历了慢性多症状状况. 这种与部署相关的条件影响了功能,但缺乏特定的暴露或物理标记.
科学领域:
- 军事医学 军事医学
- 退伍军人的健康 退伍军人的健康
- 流行病学 流行病学
背景情况:
- 与非部署人员相比,海湾战争 (GW) 退伍军人报告非特异性症状的比率更高.
- 这些症状的根本原因和临床意义尚不清楚,没有特定的疾病被确定.
研究的目的:
- 为了确定美国空军GW退伍军人报告的症状的病例定义.
- 描述临床表现并确定与这些症状相关的危险因素.
主要方法:
- 1995年进行了一项横截面人口调查和临床评估.
- 包括个人特征,症状,结构面试,功能评估 (SF-36),精神病学查,体检和实验室/血清学测试.
- 调查涉及3723名空军现役志愿者;临床评估包括158名华退伍军人.
主要成果:
- 一个病例是由疲劳,情绪认知或肌肉骨类别的慢性症状定义的.
- 轻度至中度和严重病例的患病率在GW退伍军人 (39%和6%) 与非部署人员 (14%和0.7%) 相比显著更高.
- 没有特定的部署暴露与疾病有关;然而,尽管身体/实验室发现正常,但病例显示功能和幸福感下降.
结论:
- 一种慢性多症状状况与在现役空军人员中部署GW有显著的关联.
- 这种情况与特定的GW暴露无关,并且也发生在非部署的个体中.
- 这表明一个复杂的病因学超出了直接的战时暴露.
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