在单个附属体的分段和上升附属体中,局部控制信息流
J Lomelí1, J Quevedo, P Linares
1Department of Physiology, Biophysics and Neurosciences, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional, México DF, México.
Nature
|October 23, 1998
概括
脊髓GABA内部神经元可以选择性地控制感官信息. 前突触抑制允许不同 afferent 纤维分支的独立调制,从而实现有针对性的神经通信.
科学领域:
- 神经科学是一个神经科学.
- 脊髓生理学 脊髓生理学
- 感官处理 感官处理
背景情况:
- 脊椎动物的脊髓GABA内部神经元介导感官 afferents的前突触抑制.
- 这种在单个附属体的明显的脊髓内分支上进行的前突触控制的选择性仍然不清楚.
研究的目的:
- 为了研究在单个肌肉 afferents的前突触控制的局部性质.
- 为了确定是否可以独立调节 afferents 的分段和上升附带.
主要方法:
- 同时测量来自同一个肌肉旋转轴的两个脊内附带的初级附带脱极化.
- 从结束在L6-L7并上升到L3 (克拉克列) 的抵押品记录.
主要成果:
- 存在中央机制,独立控制分段和上升抵押的突触效率.
- 焦点前突触抑制可以使脊髓内 afferent 分枝的分化.
结论:
- 选择性前突触抑制可使动态,分成部分控制感官信息流.
- 这种机制可能会将从一个共同的感官来源接收输入的脊髓后联触点解.
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