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Reverse Yeast Two-hybrid System to Identify Mammalian Nuclear Receptor Residues that Interact with Ligands and/or Antagonists
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安德罗斯坦代谢产物与核受体CAR-beta结合并使其失活

B M Forman1, I Tzameli, H S Choi

  • 1The City of Hope National Medical Center, Duarte, California 91010, USA. bforman@gte.net

Nature
|October 23, 1998
PubMed
概括

构成性安德罗斯坦受体-β (CAR-β) 活性被特定的安德罗斯坦类固醇抑制. 这些类固醇作为反向激动剂,逆转CAR-β.

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