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霍尔丹的规则在缺乏半半圆形X的种群中
1Department of Biology, University of Rochester, Rochester, NY 14627, USA.
概括
哈尔丹法则解释了为什么XY杂交品种往往是无菌的. 在缺少半性性染色体的蚊子上进行的新研究表明,它们遵循不孕不育的规则,但不遵循不孕不育的规则,支持现有理论.
科学领域:
- 进化生物学是进化的生物学.
- 遗传学 是一个遗传学.
- 规格 规格 规格 规格
背景情况:
- 哈尔丹规则认为异性异性 (XY) 的杂交物更容易患不孕或不活力.
- 现有的理论依赖于XY个体中X链接基因的半双相性,其中Y染色体在很大程度上是惰性的.
- 这种半双相性是理解规则遗传基础的基石.
研究的目的:
- 调查哈尔丹规则在偏离典型半性性别确定系统的物种中的适用性.
- 测试该规则是否适用于具有非半性性染色体的动物的无菌性和无活性.
主要方法:
- 在蚊子中研究了哈尔丹规则,蚊子在两种性别中都有两个功能性染色体,因此缺乏半双相性.
- 与表现出标准半 X 染色体系统的相关群体进行了比较.
- 在两组中评估了杂交不育性和不活力.
主要成果:
- 缺少半杂交的蚊子种类表现出哈尔丹对混合不育的规则,但不表现出不活性的规则.
- 一个带有半 X 染色体的相关群体遵守了哈尔丹对不育性和不可活性的规则.
- 这些差异性结果为进化遗传理论提供了关键数据.
结论:
- 这些发现支持了哈尔丹统治的更快的男性和统治理论.
- 表明半双相性对于哈尔丹规则的不可行性方面至关重要,但不一定对不孕不育.
- 突出了性别染色体系统在塑造生殖隔离的复杂性.
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相关概念视频
Pedigree Analysis
Overview
X-linked Traits
In most mammalian species, females have two X sex chromosomes and males have an X and Y. As a result, mutations on the X chromosome in females may be masked by the presence of a normal allele on the second X. In contrast, a mutation on the X chromosome in males more often causes observable biological defects, as there is no normal X to compensate. Trait variations arising from mutations on the X chromosome are called “X-linked”.
X and Y Chromosomes
Among mammals, the gender of an organism is determined by the sex chromosomes. Humans have two sex chromosomes, X and Y. Every human diploid cell has 22 pairs of autosomes and one pair of sex chromosomes. A human female has two X chromosomes, while a male has one X chromosome and one Y chromosome.
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
The germline cells such as egg and sperm cells carry only half the number of chromosomes, i.e., 22 autosomes and one sex chromosome. All eggs have an X chromosome, while sperm cells can carry an X or...
The Ratio of X Chromosome to Autosomes
In most organisms, sex is determined by the ratio of X and Y chromosomes. However, in some organisms, such as Drosophila and C.elegans, sex is determined by the ratio of the number of X chromosomes to the number of sets of autosomes. The Y chromosome in Drosophila is active but does not determine sex. It contains genes responsible for the production of sperms in adult flies.
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
Normal male Drosophila has a ratio of one X chromosome to two sets of autosomes. In contrast, normal female Drosophila...
X-linked Traits
In most mammalian species, females have two X sex chromosomes and males have an X and Y. As a result, mutations on the X chromosome in females may be masked by the presence of a normal allele on the second X. In contrast, a mutation on the X chromosome in males more often causes observable biological defects, as there is no normal X to compensate. Trait variations arising from mutations on the X chromosome are called “X-linked”.
Dosage Compensation
In animals, gender is determined by the number and type of sex chromosome. For example, human females have two X chromosomes, and males have one X and one Y chromosome, whereas C.elegans with one X chromosome is a male, and the one with two X chromosomes is a hermaphrodite.
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with distinct numbers of X chromosomes will have...
In addition to sexual development, the X chromosome has genes involved in autosomal functions such as brain development and the immune system. Therefore, males and females with distinct numbers of X chromosomes will have...