心肌梗塞后的死亡率和轻度至中度饮酒量
J Muntwyler1, C H Hennekens, J E Buring
1Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.
Lancet (London, England)
|December 24, 1998
概括
轻度到中度的酒精消费与男性心肌梗塞病史中较低的总死亡率有关. 这项研究表明,适度饮酒在这个患者群体中具有潜在的保护作用.
科学领域:
- 心血管健康 心血管健康
- 流行病学 流行病学
- 酒精研究 酒精研究
背景情况:
- 过度饮酒与死亡率的增加有关.
- 轻度至中度饮酒可能会降低健康个体的死亡率.
- 关于酒精对心肌梗塞后患者死亡率的影响的数据有限.
研究的目的:
- 调查轻度至中度饮酒与先前心肌梗塞的男性死亡率之间的关系.
- 为了解决这一特定患者群体数据的稀缺性.
主要方法:
- 这项前性研究涉及来自医生健康研究的90,150名男性.
- 包括5358名先前患有心肌梗塞的男性,没有癌症,中风或肝病史.
- 使用食物频率问卷估计的酒精消耗.
主要成果:
- 平均5年的随访观察到920例死亡.
- 在混调整后,中度饮酒量显示总死亡率显著下降 (p=0.016).
- 随着中度酒精摄入量增加,总死亡率的相对风险下降 (例如,0.72为2-4杯/周).
结论:
- 曾经患有心肌梗塞的男性,饮用少量至中量的酒精,总死亡率较低.
- 研究结果表明,在这个群体中,轻度到中度的酒精消费可能有助于生存.
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