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老年女性冲动性尿失禁的行为与药物治疗:一项随机对照试验
K L Burgio1, J L Locher, P S Goode
1Department of Medicine, School of Medicine, University of Alabama at Birmingham, USA. Kburgio@Aging.dom.uab.edu
JAMA
|December 24, 1998
概括
在老年妇女中,生物反辅助行为治疗显著减少了尿失禁发作,比药物治疗或安慰剂更有效. 这种安全,保守的干预建议作为一线治疗.
科学领域:
- 老年医学 老年医学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 行为科学 行为科学
背景情况:
- 尿失禁 (UI) 是一种普遍影响许多老年人的疾病,有多种不同的因素和可用的治疗方法.
- 有效的管理策略对于改善社区居住的老年妇女的生活质量至关重要.
研究的目的:
- 为了比较生物反辅助行为治疗与药物治疗和安慰剂对冲动和混合尿失禁的疗效.
- 评估患者对尿失禁不同治疗方式的感知改善和满意度.
主要方法:
- 一个随机的,安慰剂对照试验,涉及197名年龄在55-92岁的妇女,尿动力学确认的冲动或混合UI.
- 参与者接受了为期8周的生物反辅助行为治疗,氧丁宁化物药物或安慰剂.
- 结果包括减少失禁情节 (膀日记) 和患者报告的改善和满意度指标.
主要成果:
- 行为治疗实现了80.7%的失禁事件减少,明显优于药物治疗 (68.5%) 和安慰剂 (39.4%).
- 与药物 (50.9%) 和安慰剂 (26.9%) 相比,患者对改善的感知是行为治疗 (74.1%"更好") 最高的.
- 较少的行为治疗患者希望改变 (14.0%) 与药物或安慰剂组 (75.5%) 相比.
结论:
- 生物反辅助行为治疗是一种安全,有效和耐受良好的第一线干预措施,用于冲动和混合尿失禁.
- 对于患有尿失禁的老年妇女,建议增加行为干预措施的可用性.
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