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Updated: Jul 10, 2026

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair
10:59

Atomic Force Microscopy Investigations of DNA Lesion Recognition in Nucleotide Excision Repair

Published on: May 24, 2017

限制内核酶在完整的牛核中对卫星DNA的裂变

L Lipchitz, R Axel

    Cell
    |October 1, 1976
    PubMed
    概括

    DNA限制内核酶EcoRI裂变揭示了核细胞的可访问性. 只有33%的牛卫星IDNA在完整的细胞核中被分裂,这表明在染色质结构中具有显著的位置可访问性.

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    DNA Damage can Stall the Cell Cycle02:36

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    In response to DNA damage, cells can pause the cell cycle to assess and repair the breaks. However, the cell must check the DNA at certain critical stages during the cell cycle. If the cell cycle pauses before DNA replication, the cells will contain twice the amount of DNA. On the other hand, if cells arrest after DNA replication but before mitosis, they will contain four times the normal amount of DNA. With a host of specialized proteins at their disposal,cells must use the right protein at...
    Restarting Stalled Replication Forks02:37

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    DNA Damage Can Stall the Cell Cycle02:36

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