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Study on the composition of casein from individual human milks
Biomedicine / [Publiee Pour L'A.A.I.C.I.G.]
|September 30, 1976
Summary
Human whole casein exhibits significant heterogeneity in its chemical composition, particularly in phosphorus and sugar content. Post-birth milk samples show reduced amino-sugars in casein, indicating compositional changes.
Area of Science:
- Biochemistry
- Human milk composition
Background:
- Human whole casein is a complex protein mixture.
- Understanding casein heterogeneity is crucial for nutritional and clinical applications.
Purpose of the Study:
- To investigate the heterogeneity of human whole casein.
- To analyze the variability in phosphorus and sugar content.
- To examine changes in casein composition after childbirth.
Main Methods:
- Electrophoresis of 21 human whole casein samples.
- Chemical analysis of phosphorus and sugar content.
- Statistical analysis of compositional data.
Main Results:
- Significant heterogeneity was confirmed across human whole casein samples.
- Considerable variability in phosphorus and sugar content was observed.
- A correlation between different sugar components of casein was statistically demonstrated.
- A decrease in casein amino-sugars was noted in milk samples post-birth.
Conclusions:
- Human whole casein composition is highly variable.
- Post-partum changes affect casein's sugar moieties.
- Further research into casein's functional implications is warranted.