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Updated: Oct 24, 2026

Recording Light-evoked Postsynaptic Responses in Neurons in Dark-adapted, Mouse Retinal Slice Preparations Using Patch Clamp Techniques
Published on: February 11, 2015
Through a shade darkly
1Midwest Eye Institute, and Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, USA.
Abstract:
A 43-year-old man complained of difficulty seeing in dim light (nyctalopia). A prolonged photostress test and abnormal electroretinogram confirmed retinal rather than optic nerve dysfunction. Vitamin A deficiency secondary to remote ileal-jejunal bypass was diagnosed, and his visual symptoms and signs reversed with oral vitamin A supplementation.
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