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[Cytomegalovirus enteritis in AIDS. 2 cases].

M L Uffredi1, S Fournier, M Lemann

  • 1Clinique des Maladies Infectieuses et Tropicales, Hôpital Saint-Louis, Paris.

Presse Medicale (Paris, France : 1983)
|February 23, 1999
PubMed
Summary

Cytomegalovirus (CMV) infection in AIDS patients rarely affects only the small bowel. Early diagnosis and treatment are crucial for managing CMV enteritis, though outcomes can be poor.

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Area of Science:

  • Infectious Diseases
  • Gastroenterology
  • Virology

Background:

  • Cytomegalovirus (CMV) infection is a significant opportunistic infection in individuals with Acquired Immunodeficiency Syndrome (AIDS).
  • CMV manifestations typically involve multiple organs, making isolated small bowel involvement uncommon.

Observation:

  • Two human immunodeficiency virus (HIV)-positive patients presented with CMV infection exclusively localized to the small intestine.
  • These patients experienced frequent recurrences of CMV enteritis despite receiving medical treatment.

Findings:

  • Clinical symptoms including diarrhea, fever, vomiting, and abdominal pain are indicative of CMV enteritis in AIDS patients.
  • Diagnosis is confirmed through small bowel imaging studies and histopathological examination of biopsy samples.

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  • Treatment strategies involve a combination of intravenous anti-CMV medications and surgical intervention, such as partial bowel resection.

    • Implications:

    • Prompt recognition of CMV enteritis is essential for timely intervention in AIDS patients.
    • The condition's potential for recurrence and late diagnosis contributes to a generally unsatisfactory prognosis.
    • Further research into optimizing treatment protocols and early diagnostic methods for CMV enteritis is warranted.