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Optic gliomas.

M D Hollander1, M FitzPatrick, S G O'Connor

  • 1Department of Radiology, Thomas Jefferson University Hospital, Philadelphia, Pennsylvania, USA.

Radiologic Clinics of North America
|February 23, 1999
PubMed
Summary
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Optic nerve gliomas (ONGs) are the most common primary optic nerve tumors, frequently diagnosed in children. This review covers ONG anatomy, imaging, and clinical signs.

Area of Science:

  • Neuro-oncology
  • Ophthalmology
  • Pediatric Oncology

Background:

  • Primary optic nerve tumors are rare.
  • Optic nerve gliomas (ONGs) constitute 66% of these tumors.
  • ONGs predominantly affect children, with 75% diagnosed in the first decade and 90% by the second decade of life.

Purpose of the Study:

  • To provide a comprehensive overview of optic nerve gliomas (ONGs).
  • To discuss the relevant anatomy and imaging techniques for the optic pathway.
  • To outline the clinical manifestations associated with ONGs.

Main Methods:

  • Literature review focusing on optic nerve gliomas.
  • Synthesis of information regarding optic pathway anatomy and imaging.
  • Compilation of clinical presentations of ONGs.

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Main Results:

  • Optic nerve gliomas are the most frequent primary tumors of the optic nerve.
  • The majority of ONGs are diagnosed in pediatric patients within the first two decades of life.
  • Understanding optic pathway anatomy and imaging is crucial for diagnosis.

Conclusions:

  • Optic nerve gliomas are a significant concern in pediatric neuro-oncology.
  • Early diagnosis and understanding of clinical manifestations are vital for patient management.
  • This review serves as a resource for clinicians managing ONGs.