Related Experiment Videos
Esophageal-directed pressure support ventilation in normal volunteers
M Barnard1, A Shukla, T Lovell
1Department of Anaesthesia, University College London Medical School, UK.
Chest
|February 23, 1999
Summary
Esophageal-directed pressure support (EDPS) reliably triggers inspiratory pressure support (IPS) using esophageal pressures (Pes). EDPS significantly reduces the work of breathing compared to conventional IPS.
Area of Science:
- Respiratory Physiology
- Mechanical Ventilation
Background:
- Conventional inspiratory pressure support (IPS) ventilation relies on patient effort detection.
- Esophageal pressure (Pes) offers a direct measure of respiratory muscle effort.
- Optimizing ventilator triggering and support based on Pes may improve patient-ventilator synchrony.
Purpose of the Study:
- To evaluate the reliability of triggering and targeting IPS using esophageal pressures (Pes).
- To compare the work of breathing and inspiratory flow initiation time between conventional IPS and esophageal-directed pressure support (EDPS).
Main Methods:
- Prospective laboratory study involving five healthy volunteers.
- Measurements included Pes, airway pressure, and inspiratory flow.
- Ventilation was delivered via a full facemask using both conventional IPS and EDPS targeting Pes of 0 cm H2O.
Main Results:
- EDPS successfully initiated supported breathing based on Pes.
- The pressure-time product (PTP) of Pes, a measure of work of breathing, was significantly lower during EDPS compared to conventional IPS.
- Peak Pes and PTP increased with external resistances, but EDPS maintained reduced work of breathing.
Conclusions:
- Initiating supported breathing using esophageal pressure (Pes) is feasible.
- Esophageal-directed pressure support (EDPS) reduces the work of breathing more effectively than conventional IPS.
- EDPS represents a promising approach for improving patient-ventilator interaction.