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Effect of doxycycline on the apical seal of retrograde filling materials
1Department of Restorative Dentistry, University of California, San Francisco 94143-0758, USA.
Journal of the California Dental Association
|February 25, 1999
Abstract:
In this study, we examined the effect of doxycycline hydrochloride (DH) on the apical seal. Results indicated that teeth that were retrofilled with IRM or amalgam following doxycycline irrigation had significantly less dye penetration (p < 0.05). Due to its antimicrobial activity, smear layer removal ability, and improvement of apical seal, doxycycline solution may be used as an irrigant.
