[Animal experimental tests of a new filling material (Isocap)]

An experimental investigation with animals (Rhesus monkeys) concerning pulp tolerance to two premeasured dosages of calcium hydroxide cement (Reocap and Reocap-E) as well as a pre-measured dosage of filling material (Isocap) in an injection capsule was carried out (78 class V cavities). As with the negative controls, a very slight reaction, or none at all, developed in response to the two calcium hydroxide cements and the new filling material, with and without application of capping material. When five other accidentally exposed pulpae were dissected, direct capping under the corresponding preconditions (punctate exposed pulpa, longer storage period for calcium hydroxide cement) showed the characteristic formation of reparative dentin.