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[Hemodynamic-kinetic controlled extracorporeal circulation in heart surgery]
S Waldhans1, S Kasseckert, S Vogt
1Klinik für Herzchirurgie, Herzzentrum Marburg.
Biomedizinische Technik. Biomedical Engineering
|February 26, 1999
Summary
Pulsatile extracorporeal perfusion optimizes heart-lung machine function by controlling blood flow energy. This approach minimizes postoperative complications by mimicking physiological circulation, enhancing organ perfusion.
Area of Science:
- Cardiovascular physiology
- Biomedical engineering
- Fluid dynamics
Context:
- Extracorporeal perfusion aims to mimic physiological circulatory characteristics.
- Pulsatile blood flow is employed to mitigate postoperative complications.
- Heart-lung machines transmit kinetic energy to the arterial system, impacting organ perfusion and endothelial health.
Purpose:
- To investigate methods for optimizing energy release from heart-lung machines.
- To adapt blood flow in extracorporeal circulation to physiological requirements.
- To introduce and utilize the "energy-equivalent pressure" (EEP) for functional optimization.
Summary:
- A Doppler flow probe and blood pressure measurements on the ascending aorta were used to monitor extracorporeal circulation.
- Blood flow energy released by the heart-lung machine was calculated from pressure-flow curves.
- Functional parameters of a new generation of heart-lung machines were regulated, establishing a 20% rise phase within the pulse cycle and limiting energy increase to 150 joules per cycle.
Impact:
- Optimized heart-lung machine functioning through the "energy-equivalent pressure" (EEP).
- Physiological adaptation achieved with a basic flow of 60%, pulse rate of 60/min, and pulse duration of 35%.
- Potential to reduce complications associated with non-physiological blood flow during cardiopulmonary bypass.