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Bladder involvement in Behçet's syndrome.
B Cetinel1, H Akpinar, I Tüfek
1Department of Urology, Istanbul University, Cerrahpaşa School of Medicine, Turkey.
The Journal of Urology
|February 26, 1999
Summary
Behçet's syndrome can cause various voiding dysfunctions due to neurological or direct bladder issues. Augmentation ileocystoplasty is effective for severe bladder involvement in Behçet's patients.
Area of Science:
- Urology
- Rheumatology
- Pathology
Background:
- Behçet's syndrome is a multisystemic inflammatory disorder.
- Bladder involvement in Behçet's syndrome can lead to significant lower urinary tract symptoms.
Purpose of the Study:
- To describe the clinical experience with Behçet's syndrome and its impact on bladder function.
- To evaluate the diagnostic methods and treatment outcomes for patients with Behçet's syndrome and bladder involvement.
Main Methods:
- Retrospective evaluation of 8 patients (7 men, 1 woman) with Behçet's syndrome.
- Clinical assessment including history, physical examination, urinalysis, excretory urography, urodynamic studies, urethrocystoscopy, and bladder biopsies.
- Histopathological examination of bladder tissues.
Main Results:
- Common findings included detrusor overactivity and poor bladder compliance.
- Histopathology revealed thickened bladder vessel walls, lymphocytic vascular reactions, and vasculitis.
- Surgical intervention (augmentation ileocystoplasty) was performed in 3 patients.
Conclusions:
- Voiding dysfunction in Behçet's syndrome can stem from neurological or direct bladder pathology.
- Augmentation ileocystoplasty is a viable treatment for severe bladder manifestations of Behçet's syndrome.
- Comprehensive evaluation is crucial for managing bladder dysfunction in Behçet's syndrome.