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Gliclazide
M Parvez1, M S Arayne, M K Zaman
1Department of Chemistry, University of Calgary, Alberta, Canada. parvez@acs.ucalgary.ca
Acta Crystallographica. Section C, Crystal Structure Communications
|February 27, 1999
Abstract:
The crystal structure of gliclazide, N-[(perhydrocyclopenta [c]pyrrol-2-yl)aminocarbonyl]-p-toluenesulfonamide, C15H21B3O3S, a second-generation oral hypoglycemic agent, contains discrete molecules with normal molecular dimensions. Both of the five-membered fused rings adopt envelope conformations. The molecules are linked into chains by intermolecular hydrogen bonds involving amino-H atoms, with N...O separations of 2.967 (3) and 2.949 (3) A.