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Related Concept Videos

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

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Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
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Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

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In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
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Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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Obesity01:24

Obesity

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The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in...
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Multidisciplinary Approach to Obesity Management: A Case Report
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Obesity surgery in Russia.

Y I Yashkov1, N M Kuzin, Y I Sedletsky

  • 1Russian Research Center of Moscow, Russia.

Obesity Surgery
|March 5, 1999
PubMed
Summary

Obesity surgery is underutilized in Russia, with simple procedures like gastric banding being more common than complex ones. The adoption of laparoscopic techniques is emerging and expected to grow.

Area of Science:

  • Bariatric Surgery
  • Obesity Epidemiology

Background:

  • Russia faces a high prevalence of overweight (40%) and obese (26%) individuals.
  • Limited data exists on the landscape of obesity surgery within Russia.

Purpose of the Study:

  • To investigate the current status and trends of bariatric surgery in Russia.
  • To identify the types and frequency of procedures performed.

Main Methods:

  • A comprehensive literature search was conducted.
  • Interviews with experienced bariatric surgeons in Russia were performed.

Main Results:

  • Jejunoileal bypass (JIB) was historically used but largely abandoned.
  • Gastric banding is prevalent, with over 545 procedures reported since 1984, increasingly utilizing laparoscopic adjustable gastric banding.

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  • Vertical banded gastroplasty (VBG) and gastric bypass procedures are performed less frequently; biliopancreatic diversion data is unavailable.
  • Conclusions:

    • Current bariatric surgery rates in Russia are insufficient to meet population needs.
    • Simpler surgical procedures dominate over more complex ones.
    • The utilization of laparoscopic approaches in bariatric surgery is nascent but anticipated to increase.