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Chick Barx2b, a marker for myogenic cells also expressed in branchial arches and neural structures

D M Smith1, C J Tabin

  • 1Department of Genetics, Harvard Medical School, 200 Longwood Avenue, Boston, MA 02115, USA.

Mechanisms of Development
|March 12, 1999
PubMed

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Determination01:51

Determination

During embryogenesis, cells become progressively committed to different fates through a two-step process: specification followed by determination. Specification is demonstrated by removing a segment of an early embryo, “neutrally” culturing the tissue in vitro—for example, in a petri dish with simple medium—and then observing the derivatives. If the cultured region gives rise to cell types that it would normally generate in the embryo, this means that it is specified. In contrast, determination...