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Primary subcutaneous mucormycosis (zygomycosis): a case report
M S Vadmal1, K Y Chung, S I Hajdu
1Department of Laboratories, North Shore University Hospital, Manhasset, NY 11030, USA.
Annals of Clinical and Laboratory Science
|March 13, 1999
Summary
A rare case of subcutaneous mucormycosis occurred in an immunocompetent patient. This fungal infection presented as a leg mass, highlighting unusual histomorphological features without predisposing factors.
Area of Science:
- Mycology
- Dermatopathology
- Infectious Diseases
Background:
- Mucormycosis is a rare, severe fungal infection.
- Typically affects immunocompromised individuals.
- Subcutaneous form is less common and often associated with risk factors.
Observation:
- A subcutaneous mass on the left leg of an immunocompetent individual.
- Initial diagnosis: non-specific foreign body granulomatous process.
- Recurrence of the mass after one year.
Findings:
- Histopathology revealed partly degenerated fungal hyphae.
- Associated inflammation: acute necrotizing and chronic granulomatous.
- Unique histomorphological presentation of primary subcutaneous mucormycosis without predisposing factors.
Implications:
- This case expands the clinical spectrum of mucormycosis.
- Highlights the importance of considering mucormycosis in unexplained subcutaneous lesions.
- Suggests mucormycosis can occur in immunocompetent hosts without apparent risk factors.