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11-Isopropylcryptolepine: A novel alkaloid isolated from cryptolepis sanguinolenta characterized using submicro NMR
1Pharmacia & Upjohn, Pharmaceutical Development, Rapid Structure Characterization Group, Kalamazoo, Michigan 49001-0199, Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, Al-Azhar University, Nasr City, Cairo, Egypt,
Abstract:
A new alkaloid has been isolated from extracts of the West African plant Cryptolepis sanguinolenta and identified by submicro NMR techniques as 11-isopropylcryptolepine (1). The unusual incorporation of the isopropyl group at the 11-position of the indolo[3,2-b]quinoline nucleus is suggestive of a mixed biosynthetic origin for the alkaloid.
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