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Thrombotic carotid megabulb: fibromuscular dysplasia, septae, and ischemic stroke
N Kubis1, D Von Langsdorff, C Petitjean
1Department of Neurology, Hôpital Lariboisière, Paris, France.
Neurology
|March 17, 1999
Abstract:
The proximal internal carotid artery is most commonly spared in cerebral fibromuscular dysplasia. The authors report the cases of three young black patients with stroke and carotid megabulbs with fibrous components, two of whom had superimposed thrombi.
Insights
Cerebral fibromuscular dysplasia typically spares the internal carotid artery. However, three young patients experienced stroke due to carotid megabulbs with fibrous tissue, and two had blood clots.
Area of Science:
- Vascular Neurology
- Cardiovascular Medicine
- Radiology
Background:
- Cerebral fibromuscular dysplasia (FMD) is a non-atherosclerotic vascular disease.
- The proximal internal carotid artery is usually unaffected in FMD.
Purpose of the Study:
- To report unusual cases of stroke in young patients associated with carotid megabulbs and FMD.
Main Methods:
- Case series reporting on three young black patients.
- Clinical presentation, imaging findings (including fibrous components and thrombi), and outcomes were reviewed.
Main Results:
- All three patients presented with stroke.
- Carotid megabulbs with fibrous components were identified in all cases.
- Two patients had superimposed thrombi within the carotid megabulbs.
Conclusions:
- Carotid megabulbs with fibrous components may be an under-recognized manifestation of FMD, particularly in young Black individuals.
- This presentation can lead to stroke due to superimposed thrombi.