Related Experiment Video
Updated: Aug 19, 2026
Optical Coherence Tomography: Imaging Mouse Retinal Ganglion Cells In Vivo
Published on: September 22, 2017
Differentiation of degenerative retinoschisis from retinal detachment using optical coherence tomography
M Ip1, C Garza-Karren, J S Duker
1Retina Service, New England Eye Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.
Objective:
To assess the potential of optical coherence tomography (OCT) to differentiate retinoschisis from retinal detachment. Optical coherence tomography is a noninvasive, noncontact imaging method that produces high-resolution, cross-sectional images of ocular tissue.
Design:
Retrospective case series.
Participants:
Thirteen eyes of 12 patients with the differential diagnosis of retinoschisis versus retinal detachment.
Methods:
Differentiation between retinoschisis and retinal detachment was established from both ophthalmoscopic and OCT examinations.
Main Outcome Measure:
Ability of OCT to differentiate retinoschisis from retinal detachment was measured.
Results:
Thirteen eyes of 12 patients with retinal elevation were examined with OCT. The cross-sectional view produced by OCT was effective in distinguishing retinoschisis from retinal detachment. Optical coherence tomography images of retinoschisis show a splitting of the neurosensory retina. The OCT images of retinal detachment show separation of full-thickness neurosensory retina from the retinal pigment epithelium band. The OCT images correlated with the clinical impression in all 13 cases.
Conclusions:
Based on this series of cases, OCT is a potentially useful new test that may be used to distinguish retinoschisis from rhegmatogenous retinal detachment.
