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Acute renal failure in pregnancy.

J H Poole1, M S Thorsen

  • 1Department of Obstetrics and Gynecology, Carolinas Medical Center, Charlotte, North Carolina 28277-8896, USA. JudithHPoole@compuserve.com

MCN. the American Journal of Maternal Child Nursing
|March 20, 1999
PubMed
Summary

Acute renal failure (ARF) in pregnancy is rare but challenging. Pregnancy alters kidney function, complicating ARF assessment and requiring careful monitoring of maternal and fetal well-being.

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Area of Science:

  • Obstetrics and Gynecology
  • Nephrology
  • Perinatal Nursing

Background:

  • Acute renal failure (ARF) in pregnancy presents unique diagnostic and management challenges.
  • Physiological changes in pregnancy, such as hydronephrosis and hydroureter, alter standard renal assessment parameters.
  • Urinary stasis and enhanced filtration during pregnancy can lead to misleading laboratory values (e.g., lower BUN and serum creatinine).

Purpose of the Study:

  • To highlight the complexities of diagnosing and managing ARF in pregnant women.
  • To emphasize the importance of understanding pregnancy-induced renal alterations for accurate assessment.
  • To underscore the critical role of perinatal nurses in monitoring maternal and fetal status.

Main Methods:

  • Review of physiological changes in pregnancy affecting renal function.

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  • Analysis of how these changes impact ARF assessment and laboratory interpretation.
  • Discussion of maternal and fetal risks associated with ARF during pregnancy.
  • Main Results:

    • Pregnancy significantly alters baseline renal function and laboratory values, complicating ARF diagnosis.
    • Physiological hydronephrosis and enhanced filtration can mask or mimic ARF.
    • Maternal risks include acidemia and fluid/electrolyte imbalances; fetal risks involve compromise due to maternal instability.

    Conclusions:

    • Accurate ARF assessment in pregnancy requires a thorough understanding of normal pregnancy physiology.
    • Perinatal nurses play a vital role in continuous maternal and fetal monitoring.
    • Changes in fetal status may be an early indicator of maternal compromise.