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Epidemiology and impact of rotavirus diarrhoea in Poland
J Z Mrukowicz1, B Krobicka, M Duplaga
1Second Department of Paediatrics, Polish-American Children's Hospital, Jagiellonian University, School of Medicine, Cracow, Poland.
Insights
Rotavirus gastroenteritis significantly impacts young children in Poland, causing severe illness and hospitalizations. Vaccination could reduce this burden and associated healthcare costs.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Rotavirus is a major cause of severe gastroenteritis in young children globally.
- Estimating the disease burden is crucial for implementing effective prevention strategies.
Purpose of the Study:
- To estimate the burden of rotavirus disease in hospitalized children in Poland.
- To assess the impact of rotavirus gastroenteritis on healthcare utilization.
Main Methods:
- Analysis of hospital and laboratory data from three Polish hospitals (1994-1996).
- Diagnosis of community-acquired and nosocomial gastroenteritis.
- Calculation of rotavirus-associated hospitalization rates and inpatient days.
Main Results:
- Rotavirus was detected in 41% of children with gastroenteritis.
- Severe gastroenteritis (score >= 11) was observed in 94% of rotavirus cases.
- Annual hospitalization rate was 3.1/1000 children (<60 months), with a mean stay of 9.5 days.
Conclusions:
- Rotavirus is a leading cause of severe gastroenteritis and hospitalization in young Polish children.
- The disease burden is substantial, indicated by estimated hospitalizations and inpatient days.
- Rotavirus vaccination presents a significant opportunity to decrease hospitalizations and healthcare costs.
Abstract:
Hospital and laboratory data were analysed in three hospitals to estimate rotavirus disease burden in 1994-96. Community acquired gastroenteritis was diagnosed in 757 children of whom 41% tested positive for rotavirus. A total of 196 children had rotavirus nosocomial infections (39% of all rotavirus community-acquired and nosocomial cases). Infants less than 24 months old and children less than 3 months old comprised 74% and 11.9% of admissions for rotavirus, respectively. Almost 94% of children with rotavirus infection had severe gastroenteritis (score > or =11). The annual rate of rotavirus associated hospitalization in Poland in 1996 was 3.1/1000 children under the age of 60 months and 5.2/1000 infants under 24 months of age. The mean hospital stay was 9.5 d (+/-9.8 d). We estimated that 8918 children under 60 months of age were hospitalized for rotavirus gastroenteritis in 1996; they accounted for 84899 inpatient days. We conclude that rotavirus is a leading aetiological agent of severe gastroenteritis in young children in Poland and that the burden of this infection is significant. Rotavirus vaccine could significantly decrease the hospitalization rate and the financial impact of rotavirus gastroenteritis in Poland.
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