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Analyte specific reagents: FDA final rule and implications for your clinical flow cytometry laboratory

R L Johnson1

  • 1University of Massachusetts Medical School, Department of Pathology and Clinical Laboratories, Berkshire Medical Center, Pittsfield, 01201, USA.

Cytometry
|March 24, 1999
PubMed

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Flow Cytometry01:23

Flow Cytometry

The development of flow cytometry techniques began in 1934 with initial attempts by Andrew Moldavan, a bacteriologist who counted the cells in a flowing capillary system. Moldavan pumped cells through a capillary tube focused under a microscope for visualization. The invention of photometry allowed the measurement of differentially-stained cells, and Louis Kamentsky developed the first multiparameter flow cytometer in 1965 to identify and count the cancer cells in cervical tissue specimens.
In...