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Multifocal fibrosclerosis presenting as Grave's orbitopathy. Bilateral exophthalmos associated with retroperitoneal
R van der Pol1, M G Nieuwenhuis, M P Mourits
1Department of Ophthalmology, University Hospital Utrecht, The Netherlands.
Background:
Multifocal fibrosclerosis (MF) is a rare disease that may be misdiagnosed as Graves' orbitopathy. The combination of localisations of MF presented here has not been reported before.
Case Report:
A 44-year-old man was referred with progressive bilateral exophthalmos. CT of his chest and abdomen revealed an intrathoracic and retroperitoneal peri-aortal soft-tissue process with hydronephrosis. Histological examination of orbital masses showed a fibrous process with low inflammatory activity. Later the sella was found to be involved as well. A diagnosis of MF was made.
Conclusion:
MF should be considered in the differential diagnosis of bilateral exophthalmos.