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Updated: Oct 13, 2026

DNA-Tethered RNA Polymerase for Programmable In vitro Transcription and Molecular Computation
Published on: December 29, 2021
[Cell molecular computer. IX. Coding principles in intracellular information processing]
Abstract:
Methods of coding the number and search for molecular program in a molecular computer are considered. The limited length of the nucleotide code is (see formula) where Pi -- probability of request of the given program, N -- total number of programs. Energetic expenditures for the synthesis of the code with the length l (in an ideal case without noise) E approximately 10 kT X l. Protein-nucleic recognition allows the work of the cell with almost the same expenditures on the account of Brown search in the presence of noise.
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