[Characteristics of relaxation experiments for proteins with "memory"]
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Updated: Aug 15, 2026

15N CPMG Relaxation Dispersion for the Investigation of Protein Conformational Dynamics on the µs-ms Timescale
Published on: April 19, 2021
Abstract:
Conditions of a linear relaxation experiment have been analysed for the proteins with "memory", i.e., the proteins whose stationary and equilibrium kinetic parameter values are changing but slowly after external perturbation. It is shown that to measure the equilibrium kinetic characteristics of these molecules one should decrease the degree of the external perturbation till the coincidence of the shape of the relaxation curves between stationary and equilibrium states after switching on and off the perturbation.
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