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Primary intracranial squamous cell carcinoma--case report.
S Murase1, H Yamakawa, A Ohkuma
1Department of Neurosurgery, Gifu University School of Medicine.
Neurologia Medico-Chirurgica
|March 27, 1999
Summary
Primary intracranial squamous cell carcinoma (SCC) developed in a patient with a history of epidermoid cyst removal. Treatment involved surgery, chemotherapy, and radiosurgery, resulting in a 5-year survival.
Area of Science:
- Neurology
- Oncology
- Neurosurgery
Background:
- A 50-year-old female with a history of right cerebellopontine angle epidermoid cyst removal presented with new neurological symptoms.
- The patient had been asymptomatic for 10 years following the initial surgery.
Observation:
- Clinical presentation included right facial nerve paresis.
- Magnetic resonance imaging revealed a heterogeneous tumor with irregular margins and marked enhancement.
- The tumor was located at the right cerebellopontine angle.
Findings:
- Histological examination confirmed moderately differentiated squamous cell carcinoma (SCC).
- Subtotal tumor removal was surgically achieved.
Implications:
- This case highlights the rare occurrence of primary intracranial SCC arising after treatment for a benign cyst.
- Multimodal treatment including surgery, chemotherapy, and gamma radiosurgery can lead to favorable outcomes.
- Long-term surveillance is crucial for patients with a history of cerebellopontine angle tumors.