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[Clinical significance of blood pressure variability in hypertension]
Aim:
To specify blood pressure (BP) rhythm and variabily at 24-hour monitoring.
Materials And Methods:
24-hour BP monitoring, cardiac echocardiography, measurements of central hemodynamics and vegetative regulation of cardiac rhythm and psychic status were performed in 178 hypertensive subjects.
Results:
Progression of cardiac function impairment is associated with reduced lowering of night blood pressure and sleep variability, stable BP variability in awake patients. A close negative relationship exists between night BP fall and peripheral resistance, BP night variability and anxiety level.
Conclusion:
Decreased lowering of night BP seems to reflect morphological changes in the vascular wall, increased variability of wakeful BP reflects less exercise tolerance, that of night BP variability--of growing somatogenically conditioned sympathicotonia and associated anxiety disorders.