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Updated: Aug 8, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Congenital heart disease: six decades of progress
1Department of Pediatrics, University of Alberta, Edmonton, Canada.
Insights
Congenital heart malformations affect 1% of newborns. Advances in surgical and interventional cardiology, alongside improved diagnostics like echocardiography, offer better management for complex heart defects.
Area of Science:
- Cardiology
- Pediatric Cardiology
- Congenital Heart Disease
Background:
- Congenital heart malformations (CHMs) are prevalent, affecting approximately 1 in 100 live births.
- Significant advancements have been made in surgical and interventional cardiology for CHMs since the first successful persistent ductus arteriosus ligation.
- Neurological complications are a common concern in patients with congenital heart disease.
Purpose of the Study:
- To review the progress in surgical and interventional management of congenital heart lesions.
- To highlight current diagnostic modalities and their expanding applications.
- To discuss challenging CHMs and the prevalence of neurological complications.
Main Methods:
- Review of historical and recent advancements in surgical and interventional cardiology.
- Discussion of diagnostic imaging techniques including echocardiography, Doppler studies, transesophageal studies, and magnetic resonance imaging.
- Focus on complex congenital heart lesions and associated neurological complications.
Main Results:
- Interventional cardiology offers alternatives to surgery for numerous congenital heart lesions.
- Echocardiography with Doppler is the primary diagnostic tool, enhanced by transesophageal studies.
- Magnetic resonance imaging aids in visualizing lesions not clearly seen on echocardiography.
- Hypoplastic left heart syndrome and pulmonary atresia variants remain challenging.
Conclusions:
- Modern cardiology provides diverse and effective treatment options for congenital heart disease.
- Advanced imaging techniques improve diagnostic accuracy for complex CHMs.
- Neurological complications represent a significant area requiring continued attention in CHDs.
Abstract:
Congenital heart malformations occur in approximately 1 in 100 live births. Since Robert Gross successfully ligated a persistent ductus arteriosus 60 years ago, there has been enormous progress in the surgical management of even the most complex lesions. More recently, the interventional cardiologist armed with balloons, stents, coils, umbrellas, and laser beams is providing an alternative to surgery for many lesions. Echocardiography combined with Doppler studies is now the most informative diagnostic modality, and its usefulness is being expanded by transesophageal studies. Magnetic resonance imaging is helpful for some lesions not well visualized on echo. Some complex lesions continue to challenge caregivers, especially the hypoplastic left heart syndrome and several variants of pulmonary atresia. Neurological complications in patients with congenital heart disease are not uncommon and are the main theme of this issue.
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