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Laterality in functional brain imaging studies of schizophrenia
Schizophrenia Bulletin
|March 31, 1999
Summary
Functional neuroimaging reveals brain laterality abnormalities in schizophrenia, particularly in left hemispheric activity. These findings highlight the role of functional imaging in understanding schizophrenia
Area of Science:
- Neuroscience
- Psychiatry
- Medical Imaging
Background:
- Schizophrenia is a complex mental disorder with suspected neurobiological underpinnings.
- Brain laterality, or hemispheric specialization, is a key area of investigation in schizophrenia research.
Purpose of the Study:
- To review the application of functional neuroimaging techniques in studying brain laterality in schizophrenia.
- To highlight recent findings on hemispheric differences in schizophrenia.
Main Methods:
- Review of functional neuroimaging studies in schizophrenia research.
- Inclusion of techniques such as 133Xenon, Positron Emission Tomography (PET), Single Photon Emission Computerized Tomography (SPECT), and functional Magnetic Resonance Imaging (fMRI).
Main Results:
- Evidence suggests lateralized brain abnormalities in some schizophrenia studies.
- Findings generally implicate abnormal left hemispheric activity in schizophrenia.
Conclusions:
- Functional neuroimaging is a valuable tool for investigating neurobiological aspects of schizophrenia.
- Further application of advanced functional imaging techniques can enhance our understanding of schizophrenia's neurobiology.