Related Experiment Video
Updated: Jan 20, 2026

10:28
Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
Published on: June 30, 2016
14.0K
Trophic and tropic factors in the development of the central nervous system
I D Nagtegaal1, E A Lakke, E Marani
1Department of Physiology, University of Leiden, The Netherlands.
Archives of Physiology and Biochemistry
|April 1, 1999
Abstract
No abstract available in PubMed .
Related Concept Videos
Intrathecal Delivery of a Test Compound to the Rat Central Nervous System
607
Source: Chen, Y., et al. Intrathecal Delivery of Antisense Oligonucleotides in the Rat Central Nervous System. J. Vis. Exp. (2019)This video demonstrates the delivery of a test compound into the cerebrospinal fluid (CSF) through a catheter implanted in the lumbar spinal column of a rat model. The compound circulates along the CSF to the brain and spinal cord, enters neurons, and offers therapeutic...
607
10:28Optical Clearing of the Mouse Central Nervous System Using Passive CLARITY
14.0K
Optical clearing techniques are revolutionizing the way tissues are visualized. In this report we describe modifications of the original Clear Lipid-exchanged Acrylamide-hybridized Rigid Imaging-compatible Tissue-hYdrogel (CLARITY) protocol that yields more consistent and less expensive...
14.0K
11:28Culturing Microglia from the Neonatal and Adult Central Nervous System
28.8K
We outline methods for the efficient and quick isolation/culture of viable microglia from the neonatal cerebral cortex and adult spinal cord. The dissection and plating of cortical microglia can be accomplished within 90 minutes, with the subsequent microglial harvest taking place ~ 10 days following the initial...
28.8K
14:55Direct Intraventricular Delivery of Drugs to the Rodent Central Nervous System
61.7K
We describe a method to target drugs to the central nervous system by either implanting a catheter or performing a bolus injection into the right lateral ventricle in mice. We focus specifically on the delivery of antisense oligonucleotides. This technique is readily adaptable to other drugs and to...
61.7K
20:51Isolation of Mononuclear Cells from the Central Nervous System of Rats with EAE
16.7K
In this video we demonstrate how to isolate mononuclear cells from the central nervous system of rats with experimental autoimmune encephalomyelitis.
16.7K
02:21Generation of a Murine Model with a Central Nervous System Infection
494
This video demonstrates the generation of a mouse model with a CNS infection. A suckling pup is injected with the virus both intracranially and intraperitoneally. The virus spreads, infecting the CNS causing neuronal cell death and inflammation. The pup is assessed for symptoms of infection as the disease...
494

