Related Concept Videos

The Spindle Assembly Checkpoint02:19

The Spindle Assembly Checkpoint

The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...
The Spindle Assembly Checkpoint02:19

The Spindle Assembly Checkpoint

The spindle assembly checkpoint is a molecular surveillance mechanism ensuring the fidelity of chromosome segregation during anaphase. The checkpoint monitors the completion of all the prerequisite steps before chromosome segregation to determine whether the segregation process should proceed or be delayed.
Many proteins function together to control the spindle assembly checkpoint. Mutations affecting these proteins may allow cells to proceed into anaphase prematurely, resulting in the...
The Buckingham Pi Theorem01:09

The Buckingham Pi Theorem

The Buckingham Pi theorem provides a structured method to simplify fluid dynamics problems by reducing complex systems of variables to dimensionless terms.
Punnett Squares01:53

Punnett Squares

A Punnett square displays the possible genotypes offspring can inherit from two parental genotypes. If a trait’s inheritance pattern (e.g., dominant or recessive) is known, Punnett squares can also be used to determine the probability of inheriting a phenotype. Punnett squares are applicable in situations where trait inheritance is determined by a single gene locus and traits are independently inherited. However, they cannot predict trait probabilities for more complex genetic inheritance...
Punnett Squares01:53

Punnett Squares

A Punnett square displays the possible genotypes offspring can inherit from two parental genotypes. If a trait’s inheritance pattern (e.g., dominant or recessive) is known, Punnett squares can also be used to determine the probability of inheriting a phenotype. Punnett squares are applicable in situations where trait inheritance is determined by a single gene locus and traits are independently inherited. However, they cannot predict trait probabilities for more complex genetic inheritance...
Southern Blot02:57

Southern Blot

Agarose gel electrophoresis is very useful in separating DNA fragments by size. Running a DNA ladder containing fragments of the known length alongside the sample helps determine the approximate length of the sample DNA fragments. However, additional steps are needed to verify the sequence identity of the sample DNA fragments.
Denatured DNA fragments must be transferred onto a carrier membrane from the gel to make it accessible to a probe - a small ssDNA fragment complementary to the target DNA...