Justification and evaluation of an aminoglycoside pharmacokinetic dosing service
Related Experiment Video
Updated: Oct 24, 2026

Multiplex Therapeutic Drug Monitoring by Isotope-dilution HPLC-MS/MS of Antibiotics in Critical Illnesses
Published on: August 30, 2018
1St. Margaret Hospital and Health Centers, Hammond, IN 46320.
Abstract:
This article reviews the administrative and clinical processes and alternatives involved in justifying and implementing an aminoglycoside pharmacokinetic dosing service in a 500-bed community hospital. The methods used to document the initial problem areas and gain medical staff and administrative approval to propose alternative solutions are described. The financial and quality considerations used to justify a new clinical service to hospital administration are reviewed and the procedures employed to implement the new service are presented. Finally, the methods used to document performance of the new service are discussed.
Related Concept Videos
Estimation of k and VD of Aminoglycosides
Determination of Multiple Dosing Parameters: Steady-State, Minimum and Maximum Concentrations
Dosage Regimens: Partial Pharmacokinetic Parameters
Dosage Regimen: Individualization
Pharmacokinetics in Pediatric Patients: Drug Excretion
Determination of Multiple Dosing Parameters: Loading and Maintenance Doses
