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Multi-purpose evaluation of H2-antagonist usage.
1Cabrini Medical Center, New York 10003.
Hospital Formulary
|May 1, 1992
Summary
This study evaluated H2 antagonist use at Cabrini Medical Center. Findings informed formulary decisions, optimizing drug utilization and cost-effectiveness for cimetidine (Tagamet).
Area of Science:
- Pharmacoeconomics
- Drug Utilization Review
- Hospital Pharmacy
Background:
- H2 antagonists are commonly prescribed for acid-related gastrointestinal disorders.
- Optimizing drug use and cost-effectiveness is crucial in hospital settings.
- Cabrini Medical Center sought to evaluate its H2 antagonist prescribing patterns.
Purpose of the Study:
- To assess the indications for H2 antagonist use.
- To evaluate the appropriateness of parenteral administration and dosing intervals.
- To determine the cost-effectiveness of cimetidine (Tagamet) and inform formulary management.
Main Methods:
- Drug usage evaluation (DUE) was conducted.
- Monthly purchasing data were analyzed.
- Prescribing patterns and cost-effectiveness of cimetidine were reviewed.
Main Results:
- The study identified specific indications for H2 antagonist utilization.
- Appropriateness of parenteral therapy and dosing strategies were assessed.
- Cost-effectiveness analysis supported the P & T Committee's decision regarding cimetidine and ranitidine.
Conclusions:
- Drug usage evaluation and data analysis are effective tools for optimizing H2 antagonist therapy.
- The findings supported the formulary decision to maintain cimetidine (Tagamet) and remove ranitidine.
- This approach enhances cost-effectiveness and appropriate drug utilization in hospitals.