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Concurrent ceftazidime DUE with clinical pharmacy intervention
A U Okpara1, O M Van Duyn, T R Cate
1Ben Taub General Hospital, TX.
Hospital Formulary
|May 1, 1994
Summary
Ceftazidime use evaluation revealed 87% of cases were inappropriate. A concurrent review was conducted to identify and correct issues with this antibiotic
Area of Science:
- Pharmacology
- Infectious Diseases
- Antimicrobial Stewardship
Background:
- Ceftazidime use increased significantly at a teaching hospital.
- Rising resistance in Pseudomonas aeruginosa prompted an evaluation.
- Previous retrospective analysis indicated high rates of inappropriate use.
Purpose of the Study:
- To conduct a drug use evaluation (DUE) of ceftazidime.
- To identify problems associated with ceftazidime prescribing.
- To implement corrective actions during concurrent patient treatment.
Main Methods:
- Retrospective pilot study analysis.
- Concurrent drug use evaluation.
- Data collection on ceftazidime prescribing patterns and patient outcomes.
Main Results:
- 87% of retrospective ceftazidime use was deemed inappropriate.
- Concurrent review aimed to identify and address issues in real-time.
- Specific findings from the concurrent review are detailed in the full study.
Conclusions:
- Significant inappropriate use of ceftazidime was identified.
- Concurrent evaluation is crucial for timely intervention.
- Improved antimicrobial stewardship for ceftazidime is necessary.