Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

A synthetic membrane for testing needle penetration.

L J Pavlovich1, W L McClung, J G Thacker

  • 1Department of Plastic Surgery, University of Virginia Health Sciences Center, Charlottesville.

Journal of Applied Biomaterials : an Official Journal of the Society for Biomaterials
|July 1, 1993
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Moiré interferometry strain measurements in elastic thin membranes.

Applied optics·2010
Same author

Revolutionary advances in organic foods.

Internal and emergency medicine·2007
Same author

Resistance to adhesion formation: a comparative study of treated and untreated mesh products placed in the abdominal cavity.

Hernia : the journal of hernias and abdominal wall surgery·2004
Same author

Quantitative swab culture versus tissue biopsy: a comparison in chronic wounds.

Ostomy/wound management·2002
Same author

An instrument to measure healing in pressure ulcers: development and validation of the pressure ulcer scale for healing (PUSH).

The journals of gerontology. Series A, Biological sciences and medical sciences·2001
Same author

Comparison of the thrombogenicity of internationally available fibrin sealants in an established microsurgical model.

Plastic and reconstructive surgery·2001
Same journal

Modification of polyethylene terephthalate (Dacron) via denier reduction: effects on material tensile strength, weight, and protein binding capabilities.

Journal of applied biomaterials : an official journal of the Society for Biomaterials·1995
Same journal

Influence of fluoride on titanium in an acidic environment measured by polarization resistance technique.

Journal of applied biomaterials : an official journal of the Society for Biomaterials·1995
Same journal

Finite element analysis of crestal bone loss around porous-coated dental implants.

Journal of applied biomaterials : an official journal of the Society for Biomaterials·1995
Same journal

Immobilization of heparin oligosaccharides onto radiofrequency plasma modified pyrolytic carbon-coated graphite.

Journal of applied biomaterials : an official journal of the Society for Biomaterials·1995
Same journal

Effects of sublethal metal ion concentrations on osteogenic cells derived from bone marrow stromal cells.

Journal of applied biomaterials : an official journal of the Society for Biomaterials·1995
Same journal

Mechanical and histological fixation of hydroxylapatite-coated pyrolytic carbon and titanium alloy implants: a report of short-term results.

Journal of applied biomaterials : an official journal of the Society for Biomaterials·1995
See all related articles

A novel polyurethane substrate effectively mimics biological tissue for needle penetration testing. This stable, homogeneous material provides a reliable and sensitive alternative for evaluating needle performance and detecting changes in penetration force.

Area of Science:

  • Biomedical Engineering
  • Materials Science
  • Medical Device Testing

Background:

  • Needle performance is critical in medical procedures and is typically assessed by penetration through biological tissue.
  • Biological tissues are inherently heterogeneous, unstable, and difficult to procure, posing significant challenges for consistent and reproducible testing.
  • There is a need for a standardized, reliable, and accessible substrate for evaluating needle penetration characteristics.

Purpose of the Study:

  • To evaluate a polyurethane-based synthetic substrate as a viable alternative to biological tissue for needle penetration testing.
  • To determine the correlation between needle penetration profiles in the synthetic substrate and natural tissue.
  • To assess the sensitivity of the synthetic substrate in detecting variations in penetration force.

Related Experiment Videos

Main Methods:

  • A homogeneous, stable polyurethane substrate was developed and characterized.
  • Needle penetration tests were conducted using the synthetic substrate and compared with tests on natural biological tissue.
  • The sensitivity of the substrate was evaluated by measuring its response to a known increase in penetration force.

Main Results:

  • Needle penetration profiles through the polyurethane substrate showed a strong correlation with those observed in natural biological tissue.
  • The synthetic substrate demonstrated sufficient sensitivity to detect a 20% increase in the force required for penetration of natural tissue.
  • The polyurethane material proved to be a stable and readily available testing medium.

Conclusions:

  • The evaluated polyurethane substrate serves as a valid and effective alternative to biological tissue for needle penetration performance testing.
  • This synthetic material offers a consistent, reproducible, and sensitive platform for the development and quality control of medical needles.
  • Utilizing this substrate can streamline and improve the evaluation of needle designs and penetration mechanics.