[State of the nervous system in psoriasis patients]

In order to clarify the role of the nervous system in the development of psoriasis the authors conducted a manifold dermato-neurological, biochemical and electrophysiological (EEG, REG) study of 130 patients. In 76.4% there were different neurological disorders: vegetative-vascular disturbances, functional diseases of the nervous system. Psoriasis was also seen in combination with segulae of brain injuries, neuroinfections, hypothalamic syndrome, vascular brain lesions, epilepsy. Clinico-electrophysiological studies detected a dysfunction on all levels of the brain, mainly in the limbico-reticular complex and mesodiencephalic formation. Quite possibly the above-mentioned changes are of significance for the development of psoriasis, making the use of drugs influencing these brain structure necessary. Taking into consideration the REG data it is also necessary to use preparations influencing the vascular tone of the brain and physiotherapeutical procedures normalizing the cerebral hemodynamics.