[Use of glucocorticoid hormones in multiple sclerosis]

A long-term observation over patients with disseminated scleosis who were treated by glucorticoid hormones demonstrated that hormone therapy with short sessions and a standard scheme appeared to be uneffective. The presentation is based on an examination of 25 patients who had undergone a durative course of hormone therapy with an individual scheme of optimal doses equal to middle ones (30-40 mg of prednisolon) and a selection of maintenance doses used for a long time or with short intervals. Such forms of treatment were more effective. During treatment the authors used immunological tests and analysis of electrolytes in the blood, sugar, urea, etc. Hormone therapy is indicated in acute forms of disseminated sclerosis and in a remittent development in the stage of exacerbation in the II and III phases. Along with favourable effects in 3 patients there was a development of hormone dependency and complications.