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A test for 'hygienic' hand disinfection.

G A Ayliffe, J R Babb, A H Quoraishi

    Journal of Clinical Pathology
    |October 1, 1978
    PubMed
    Summary
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    70% alcohol, with or without chlorhexidine, proved most effective for hand disinfection against common bacteria like Staphylococcus aureus and Escherichia coli. Other tested agents showed variable efficacy, with plain soap performing similarly to some antiseptic detergents against Gram-negative bacilli.

    Area of Science:

    • Microbiology
    • Infection Control
    • Dermatology

    Background:

    • Hand hygiene is crucial in preventing pathogen transmission.
    • Assessing the efficacy of various disinfectants is essential for infection control protocols.
    • Standardized testing procedures are needed to compare antiseptic effectiveness.

    Purpose of the Study:

    • To evaluate the efficacy of different hand disinfection agents.
    • To compare the effectiveness of antiseptic-detergents, alcoholic solutions, and unmedicated soap.
    • To determine the most effective preparation for reducing microbial counts on fingertips.

    Main Methods:

    • A standardized test procedure was developed for evaluating hand disinfection.
    • Finger-tips were inoculated with broth cultures of Staphylococcus aureus, Staphylococcus saprophyticus, Escherichia coli, and Pseudomonas aeruginosa.

    Related Experiment Videos

  • Microbial counts were determined from hand washings after disinfection with various agents.

    • Main Results:

    • 70% alcohol, with or without chlorhexidine, demonstrated the highest efficacy in reducing microbial counts.
    • Antiseptic-detergents showed variable results, with some performing no better than plain soap against Gram-negative bacilli.
    • The survival rate of dried organisms on skin without disinfection was also assessed.

    Conclusions:

    • Alcohol-based solutions, particularly 70% alcohol with or without chlorhexidine, are highly effective for hand disinfection.
    • The efficacy of antiseptic-detergents can be variable, and they may not offer significant advantages over plain soap for certain bacteria.
    • Further research into optimal hand hygiene practices is warranted to combat microbial contamination.