Current concepts in the identification and treatment of stage 2 macular holes

Over the past decade, a better understanding of the pathogenesis and evolution of idiopathic macular holes has developed. Theories implicating the role of the vitreous in hole formation have led to surgical interventions that have met with surprising success. Recent advances in identifying early lesions, coupled with variations in surgical results based on the hole's preoperative stage, have led some authors to suggest earlier intervention. This report reviews current concepts of macular hole development, focusing on the pathoanatomy, natural history, surgical approach, and surgical outcomes of stage 2 macular holes.