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Updated: Aug 2, 2026

Murine Model of Wound Healing
Published on: May 28, 2013
Wound healing management: enhancing patient outcomes and reducing costs
J V Boykin1, M C Crossland, L M Cole
1Columbia Retreat Regional Wound Healing Center, USA.
Biomedical technology, including transcutaneous oxygen mapping and hyperbaric oxygen (HBO) therapy, improves non-healing wound management. Adjunctive HBO therapy in outpatient wound healing centers offers cost-effective, advanced treatment options for chronic wounds.
Area of Science:
- Biomedical engineering
- Wound healing research
- Hyperbaric medicine
Background:
- Non-healing wounds often involve complex oxygen-related pathophysiology.
- Transcutaneous oxygen mapping and hyperbaric oxygen (HBO) therapy are key biomedical technologies for wound management.
- Recent advancements enable HBO therapy in outpatient settings, facilitating cost-effective wound healing centers (WHC).
Purpose of the Study:
- To highlight the role of biomedical technology in managing non-healing wounds.
- To present a case study of successful adjunctive hyperbaric oxygen therapy for a specific wound type.
- To demonstrate the cost-effectiveness of advanced wound healing approaches.
Main Methods:
- Utilized transcutaneous oxygen mapping to evaluate wound pathophysiology.
- Administered adjunctive hyperbaric oxygen (HBO) therapy.
- Employed a multidisciplinary team approach within a wound healing center (WHC).
Main Results:
- Successfully treated a soft-tissue radiation necrosis ulceration of the leg with adjunctive HBO.
- Achieved a greater than 30% reduction in patient charges compared to traditional management.
- Demonstrated improved outcomes for a chronic wound through advanced technology and a multidisciplinary approach.
Conclusions:
- Biomedical technologies, including HBO, significantly enhance non-healing wound management.
- Outpatient HBO therapy and WHCs offer cost-effective solutions for chronic wound care.
- A multidisciplinary approach combined with advanced technology yields better patient outcomes and reduced healthcare costs.
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