Tumors of the cornea and conjunctiva

This article reviews literature regarding corneal and conjunctival tumors and explores some of the causative factors, prognostic factors, and treatment options for melanocytic, neoplastic, and lymphoid tumors. A review of epibulbar choristomas and associated syndromes is also included. Newer treatments including excimer laser phototherapeutic keratectomy and topical mitomycin C for corneal intraepithelial neoplasia, microscopic control of tissue margins with sequential surgery for squamous cell carcinoma and cryotherapy for lymphoma are reviewed and compared with traditional therapy. Conjunctival mucosal-associated lymphoid tissue (MALT) lymphoma is probably more common than previously realized. Recent findings of MALT lymphoma and the origin of conjunctival MALT is discussed.