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Related Experiment Videos

"Tail sign" associated with microembolic signals.

E Furui1, K Hanzawa, H Ohzeki

  • 1Department of Neurology, Kanazawa University, Kanazawa, Japan. efurui@med.kanazawa-u.ac.jp

Stroke
|April 3, 1999
PubMed
Summary

Tail signs (TS) following microembolic signals (MES) detected by transcranial Doppler ultrasound (TCD) are specific indicators. These signs, observed in animal and clinical studies, can improve the identification of cerebral embolism.

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Area of Science:

  • Neurosonology
  • Cerebrovascular disease
  • Medical signal analysis

Background:

  • Transcranial Doppler (TCD) ultrasound detects circulating microembolic signals (MES).
  • Tail signs (TS) are a specific signal pattern observed after MES on high time-resolution spectral displays.
  • The specificity of TS for MES requires further investigation.

Purpose of the Study:

  • To determine if tail signs (TS) are specific indicators of microembolic signals (MES).
  • To investigate the characteristics of TS in both animal models and human patients.
  • To assess the utility of TS as a criterion for MES identification.

Main Methods:

  • An animal study using pigs with venoarterial extracorporeal membrane oxygenation as a model for cerebral embolism.

Related Experiment Videos

  • Multigated transcranial Doppler (TCD) monitoring with offline analysis of MES and TS parameters.
  • Examination of TS in patients during a clinical study.

    • Main Results:

    • Tail signs (TS) followed 72.9% of investigated microembolic signals (MES) in the animal study.
    • No tail signs (TS) were associated with artifacts, indicating specificity for MES.
    • Tail signs (TS) were observed in association with MES in the clinical study, supporting their clinical relevance.

    Conclusions:

    • Tail signs (TS) are specific indicators of microembolic signals (MES).
    • TS may represent emboli traversing branch vessels or indicate vessel tortuosity.
    • TS can serve as an additional criterion for identifying MES.