Related Experiment Video
Updated: Sep 4, 2026

The Participant-Reported Implementation Update and Score (PRIUS): A Novel Method for Capturing Implementation-Related Data Over Time
Published on: February 19, 2021
Role of Clinical Trials in Implementation Science and Organization Change: An Overview of Cluster, Stepped-Wedge, and
Kelly Coughlan1,2, Oyebola Fasugba1,2, Simeon Dale1,2
1Nursing Research Institute-St Vincent's Health Network Sydney & St Vincent's Hospital Melbourne, Australia (K.C., O.F., S.D., N.S., S.M.).
Abstract:
Implementation science plays a pivotal role in advancing organizational change within stroke healthcare settings by systematically evaluating and facilitating the adoption of evidence-based practices. This topical review examines the use of key trial designs relevant to implementation science research that aim to change organizational practice, highlighting their unique design features and methodological considerations. It also provides case studies of stroke research that have used each of the methods discussed demonstrating the practical applications in real-world environments. This overview aims to guide researchers and clinicians in selecting appropriate trial designs to optimize the translation of research into sustainable organizational systems and processes.
Related Concept Videos
Clinical Trials
There are four phases in a clinical trial. A phase one...
Clinical Trials: Overview
Types of Biopharmaceutical Studies: Controlled and Non-Controlled Approaches
Non-controlled studies, commonly employed for initial exploration, lack a control group, rendering them susceptible to biases and external influences. In contrast, controlled...
Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and case-control studies.
Bioequivalence Experimental Study Designs: Repeated Measures, Cross-Over, Carry-Over, and Latin Square Designs
Nursing Implementation
The five steps to implementing effective nursing care include reassessing the patient, reviewing and revising the existing nursing care plan, organizing the resources and care delivery, anticipating and preventing complications, and implementing nursing interventions.